In this talk I will show how Chemical Engineers have an important role to play in this field, one so important for human well-being. The talk will use the liver system - the body's 'chemical factory' - where diseases like diabetes and non-alcoholic fatty liver disease are caused by problems with glucose levels affected by diet, medicines, metabolism and genetics. What is needed are systems approaches to modelling complex chemical and physical interactions at multiple scales in living systems through Chemical Engineering analysis. Engineering design techniques are increasingly needed to be able to make reliable system-wide predictions of the effects of medical interventions which are proposed by the ‘engineering design’ process. Interventions can be environmental through the introduction of chemical agents, through clinical interventions, or genetic analysis. We can also manage the range of variability that can be tolerated in the proposed environmental or clinical action and work back through using computational models to ensure that the range of variability in the data on which the model is based is of sufficient accuracy to meet the ‘design tolerance’.
David Bogle, Pro-Vice-Provost of the Doctoral School and Professor of Chemical Engineering.
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